{"id":284738,"date":"2024-10-19T19:16:41","date_gmt":"2024-10-19T19:16:41","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bs-iso-19040-32018\/"},"modified":"2024-10-25T16:06:32","modified_gmt":"2024-10-25T16:06:32","slug":"bs-iso-19040-32018","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bs-iso-19040-32018\/","title":{"rendered":"BS ISO 19040-3:2018"},"content":{"rendered":"<p>This document specifies a method for the determination of the estrogenic potential of water and waste water by means of a reporter gene assay utilizing stably transfected human cells. This reporter gene assay is based on the activation of the human estrogen receptor alpha.<\/p>\n<p>This method is applicable to:<\/p>\n<ul>\n<li>\n<p>fresh water;<\/p>\n<\/li>\n<li>\n<p>waste water;<\/p>\n<\/li>\n<li>\n<p>aqueous extracts and leachates;<\/p>\n<\/li>\n<li>\n<p>eluates of sediments (fresh water);<\/p>\n<\/li>\n<li>\n<p>pore water;<\/p>\n<\/li>\n<li>\n<p>aqueous solutions of single substances or of chemical mixtures;<\/p>\n<\/li>\n<li>\n<p>drinking water;<\/p>\n<\/li>\n<li>\n<p>the limit of quantification&nbsp;(LOQ) of this method for the direct analysis of water samples is between 0,3&nbsp;ng\/l and 1&nbsp;ng\/l 17<i>\u03b2<\/i>-estradiol equivalents&nbsp;(EEQ) based on the results of the international interlaboratory trial (see Annex&nbsp;F). The upper working range was evaluated [based on the results of the international interlaboratory trial (see Table&nbsp;F.3)] up to a level of 75&nbsp;ng EEQ\/l. Samples showing estrogenic potencies above this threshold have to be diluted for a valid quantification. Extraction and pre concentration of water samples can prove necessary if their estrogenic potential is below the given LOQ.<\/p>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p><b>Water quality. Determination of the estrogenic potential of water and waste water &#8211; In vitro human cell-based reporter gene assay<\/b><\/p>\n<table class=\"shortdes-table\" style=\"width: 100%\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>Published By<\/td>\n<td>Publication Date<\/td>\n<td>Number of Pages<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/pdfstandards.shop\/product-category\/publishers\/bsi\/\"><b>BSI<\/b><\/a><\/td>\n<td>2018<\/td>\n<td>50<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":284744,"template":"","meta":{"rank_math_lock_modified_date":false,"ep_exclude_from_search":false},"product_cat":[218,2641],"product_tag":[],"class_list":{"0":"post-284738","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-13-060-70","7":"product_cat-bsi","9":"first","10":"instock","11":"sold-individually","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product\/284738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media\/284744"}],"wp:attachment":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media?parent=284738"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_cat?post=284738"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_tag?post=284738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}